The Medical Letter TML n. 17/2016
Nr. 17 del 01/09/2016
TML n. 17/2016 – UNA NUOVA FORMULAZIONE DI LEVETIRACETAM PER L’EPILESSIA
La US Food and Drug Administration (FDA) ha approvato una formulazione in compresse a rapida disintegrazione del farmaco antiepilettico levetiracetam (Spritam-Aprecia negli USA; non disponibile in commercio in Italia) per il trattamento aggiuntivo delle crisi a esordio parziale, miocloniche e tonico-cloniche generalizzate primarie. Le formulazioni per uso orale ed endovenoso di levetiracetam (Keppra-UCB; disponibile anche come medicinale equivalente) sono disponibili da anni sia negli Usa che in Italia. Benché approvato dalla FDA solo come terapia aggiuntiva, il levetiracetam viene comunemente utilizzato come monoterapia per le crisi a esordio parziale e le crisi generalizzate e può essere efficace anche per il trattamento delle crisi di assenza e delle crisi associate alla sindrome di Lennox-Gastaut (1).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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