The Medical Letter TML n. 20/2015
Nr. 20 del 15/10/2015
TML n. 20/2015 – SACUBITRIL/VALSARTAN PER LO SCOMPENSO CARDIACO
La US Food and Drug Administration (FDA) ha approvato Entresto (Novartis in USA; il 24 settembre l’EMA ha dato parere favorevole per la commercializzazione di Entresto anche in Europa), un’associazione orale precostituita dell’inibitore della neprilisina sacubitril e dell’antagonista dei recettori dell’angiotensina (ARB) valsartan, per ridurre il rischio di morte cardiovascolare e ospedalizzazione per scompenso cardiaco nei pazienti con insufficienza cardiaca e frazione di eiezione ridotta. Il sacubitril è il primo inibitore della neprilisina a diventare disponibile negli Stati Uniti.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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