The Medical Letter TML n. 20/2015
Nr. 20 del 15/10/2015
TML n. 20/2015 – IN BREVE: Una sospensione per via enterica a base di carbidopa/levodopa per il morbo di Parkinson
La US Food and Drug Administration (FDA) ha approvato Duopa (Abbvie in USA), una sospensione per via enterica di carbidopa/levodopa, per il trattamento delle fluttuazioni motorie nei pazienti affetti da morbo di Parkinson (PD) avanzata. Il farmaco è disponibile in Europa e in Italia dal 2001 con il nome di Duodopa.
Nei pazienti con PD avanzata, lo svuotamento gastrico può essere ritardato e imprevedibile, il che può influenzare la velocità e l’entità di assorbimento della carbidopa/levodopa e la sua efficacia. Al fine di bypassare lo stomaco, la nuova formulazione viene erogata tramite un sondino nasodigiunale o una gastrostomia endoscopica percutanea con sondino nasodigiunale (PEG-J).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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