The Medical Letter TML n. 11/2014
Nr. 11 del 01/06/2014
TML n. 11/2014 – GOLIMUMAB PER LA COLITE ULCEROSA
La US Food and Drug Administration (FDA) ha approvato il golimumab (in Italia: Simponi-MSD Italia), un anticorpo monoclonale totalmente umano specifico per il fattore di necrosi tumorale alfa (TNF, tumor necrosis factor), per l’induzione e il mantenimento della remissione in pazienti con colite ulcerosa moderata-grave che non hanno risposto o che risultano intolleranti ad altre terapie o in quelli che necessitano di un trattamento continuativo con corticosteroidi. Il golimumab è stato approvato in precedenza dalla FDA per il trattamento dell’artrite reumatoide, dell’artrite psoriasica e della spondilite anchilosante (1). È il terzo inibitore del TNF approvato per l’impiego nella colite ulcerosa (2). Il golimumab è approvato anche in Italia per tutte queste indicazioni.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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