The Medical Letter TML n. 8/2014
Nr. 08 del 15/04/2014
TML n. 8/2014 – MACITENTAN PER L’IPERTENSIONE ARTERIOSA POLMONARE
La US Food and Drug Administration (FDA) ha approvato il macitentan (Opsumit-Actelion, negli USA; approvato in Europa nel dicembre 2013 e non attualmente disponibile in commercio in Italia), per il trattamento orale dell’ipertensione arteriosa polmonare (IAP). Il macitentan è il secondo antagonista non selettivo dei recettori per l’endotelina approvato per il trattamento della IAP. È un derivato del bosentan (Tracleer-Actelion Pharm. Italia), un altro farmaco prodotto da Actelion che si prevede diventerà disponibile negli Stati Uniti come farmaco generico nel 2015. Il riociguat (Adempas, negli USA), un altro nuovo farmaco approvato per la stessa indicazione, sarà trattato in un prossimo numero di The Medical Letter.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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