The Medical Letter TML n. 7/2014
Nr. 07 del 01/04/2014
TML n. 7/2014 – CERTOLIZUMAB PEGOL E USTEKINUMAB PER L’ARTRITE PSORIASICA
Il certolizumab pegol (Cimzia-UCB Pharma), un inibitore del fattore di necrosi tumorale (TNF, tumor necrosis factor) approvato inizialmente per il trattamento del morbo di Crohn (1) e dell’artrite reumatoide (2), e l’ustekinumab (Stelara-Janssen-Cilag), un antagonista dell’interleuchina umana (IL) 12 e 23 approvato inizialmente per il trattamento della psoriasi a placche moderata-grave (3), sono stati successivamente approvati dalla US Food and Drug Administration (FDA) anche per il trattamento dell’artrite psoriasica attiva.
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