The Medical Letter TML n. 5/2013
Nr. 05 del 01/03/2013
TML n. 5/2013 – TOFACITINIB PER L’ARTRITE REUMATOIDE
La US Food and Drug Administration (FDA) ha approvato il tofacitinib (Xeljanz-Pfizer, in attesa di approvazione in Europa), un inibitore della chinasi JAK (Janus-associated kinase) per somministrazione orale, per il trattamento di pazienti adulti con artrite reumatoide (AR) attiva di grado moderato-grave che non hanno risposto adeguatamente o che sono risultati intolleranti al metotrexato. Il ruxolitinib (Jakafi-Incite, negli USA; in Europa: Jakavi-Novartis, approvato in Europa il 28 agosto 2012 e di prossima commercializzazione in Italia), l’unico altro inibitore JAK disponibile negli Stati Uniti, è stato approvato dalla FDA per il trattamento della mielofibrosi (1).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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