The Medical Letter TML n. 17/2013
Nr. 17 del 01/09/2013
TML n. 17/2013 – OSPEMIFENE PER LA DISPAREUNIA
La US Food and Drug Administration (FDA) ha approvato l’ospemifene (Osphena-Shionogi; in attesa di approvazione in Europa), un agonista/antagonista degli estrogeni, per il trattamento orale della dispareunia di grado moderato-grave in donne in postmenopausa. L’ospemifene è il quarto agonista/antagonista degli estrogeni immesso in commercio negli Stati Uniti, ma è l’unico a possedere un effetto simil-estrogenico sull’epitelio vaginale. Gli altri tre, il tamoxifene (Nolvadex-AstraZeneca, e altri; disponibile anche come medicinale equivalente), il toremifene (Fareston-Schering-Plough) e il raloxifene (Evista-Daiichi Sankyo Italia; Optruma-Menarini), vengono utilizzati per il trattamento e la prevenzione del carcinoma mammario e dell’osteoporosi.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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