The Medical Letter TML n. 24/2012
Nr. 24 del 15/12/2012
TML n. 24/2012 – IN BREVE: Alendronato effervescente
Una nuova formulazione effervescente di alendronato (Binosto-Mission, negli USA) è stata recentemente approvata dalla US Food and Drug Administration (FDA) per il trattamento dell’osteoporosi. Il prodotto è stato approvato con procedura decentralizzata europea nel dicembre 2011 con il nome commerciale di Steovess (Takeda) e non è disponibile in commercio in Italia. La nuova compressa effervescente da 70 mg è considerata bioequivalente alle tradizionali formulazioni di alendronato in compresse da 70 mg (Fosamax-Merck Sharp & Dohme, e altri; disponibile anche come medicinale equivalente), che sono difficili da deglutire e possono causare lesioni esofagee (1). Non sono disponibili studi pubblicati che abbiano valutato questa nuova formulazione.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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