The Medical Letter TML n. 23/2011
Nr. 23 del 01/12/2011
TML n. 23/2011 – FIDAXOMICINA PER L’INFEZIONE DA CLOSTRIDIUM DIFFICILE
La US Food and Drug Administration (FDA) ha approvato la fidaxomicina (Dificid-Optimer, negli USA), un nuovo antibiotico macrolide per via orale, per il trattamento della diarrea associata a infezione da Clostridium difficile (ICD) in pazienti a partire dai 18 anni di età. In Europa la fidaxomicina (Dificlir-Astellas Pharma) è in attesa di approvazione definitiva dopo il parere positivo del CHMP dell’EMA del 22 settembre 2011. Negli ultimi anni si è assistito a un aumento dell’incidenza e della gravità dell’ICD a causa della comparsa di un ceppo epidemico a elevata virulenza (NAP1/B1/027), probabilmente correlato al diffuso utilizzo dei fluorochinoloni.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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