The Medical Letter n. 1 / 2021
Nr. 01 del 01/01/2021
TML n.1 / 2021 EMPAGLIFLOZIN PER L’INSUFFICIENZA CARDIACA
In uno studio clinico randomizzato controllato con placebo, l’inibitore del co-trasportatore sodio-glucosio di tipo 2 (SGLT2) empagliflozin (Jardiance–Boehringer Ingelheim) è risultato associato a una riduzione del rischio composito di morte cardiovascolare o ricovero per il peggioramento dell’insufficienza cardiaca (HF) nei pazienti affetti da insufficienza cardiaca con frazione di eiezione ridotta (HFrEF), indipendentemente dalla presenza concomitante di diabete di tipo 2. A oggi, l’empagliflozin non è approvato dalla FDA per quest’uso, mentre l’inibitore dell’SGLT2 dapagliflozin (Forxiga-Astrazeneca) è stato approvato quest’anno per questa indicazione.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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