The Medical Letter TML n. 10 / 2024
Nr. 10 del 13/05/2024
TML n. 10 / 2024 Sotatercept per l'ipertensione arteriosa polmonare
La US Food and Drug Administration (FDA) ha approvato il sotatercept (Winrevair Merck in USA; non disponibile in commercio in Italia), un inibitore della segnalazione dell'attivina, primo di questa classe, per aumentare la capacità di esercizio, migliorare la classe funzionale relativa alla classificazione dell’OMS e ridurre il rischio di aggravamento negli adulti con ipertensione arteriosa polmonare (pulmonary arterial hypertension, PAH) di gruppo 1.
TRATTAMENTO STANDARD – I farmaci approvati dalla FDA per il trattamento della PAH sono elencati nella tabella 3. È stato dimostrato che l'uso di questi farmaci, da soli o in associazione, migliora la capacità di esercizio e riduce il rischio di aggravamento nei pazienti con PAH (1,2)
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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