The Medical Letter TML n. 11/2011
Nr. 11 del 01/06/2011
TML n. 11/2011 – BUPRENORFINA TRANSDERMICA PER IL DOLORE CRONICO
La US Food and Drug Administration (FDA) ha approvato una formulazione transdermica di buprenorfina, un agonista parziale degli oppioidi (Butrans-Purdue; cerotti da 5-10-20 µg/h per sette giorni; non disponibili in commercio in Italia), per il trattamento del dolore cronico moderato-grave. La buprenorfina è disponibile da anni negli Stati Uniti in formulazioni parenterali per il dolore e in compresse sublinguali per la dipendenza da oppioidi (1). La buprenorfina transdermica è in commercio in Italia da alcuni anni (Transtec-Formenti; cerotti da 35-52,5-70 µg/h per 96 ore) (2); oltre alla formulazione transdermica, sono disponibili la formulazione parenterale e le compresse sublinguali per il dolore acuto e cronico (Temgesic-Schering-Plough), e le compresse sublinguali per la terapia sostitutiva nella dipendenza da oppioidi (Subutex-Essex Italia).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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