The Medical Letter TML n. 11/2017
Nr. 11 del 01/06/2017
TML n. 11/2017 – ACIDO OBETICOLICO PER LA COLANGITE BILIARE PRIMITIVA
L’acido obeticolico (Ocaliva-Intercept negli USA; farmaco approvato in Europa, ma non disponibile in commercio in Italia), un agonista del recettore X farnesoide, è stato approvato dalla US Food and Drug Administration (FDA) per il trattamento della colangite biliare primitiva; è indicato per l’uso in associazione all’acido ursodesossicolico (ursodiolo, UDCA; Desoxil-S.F.Group e altri; disponibile anche come medicinale equivalente) negli adulti con una risposta inadeguata all’UDCA e in monoterapia negli adulti che non tollerano il trattamento con l’UDCA. L’acido obeticolico è il secondo farmaco a essere approvato per questa indicazione; l’UDCA è stato il primo.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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