The Medical Letter TML n. 13/2020
Nr. 13 del 01/07/2020
TML n. 13/2020 DEPRESSIONE RESPIRATORIA CON I GABAPENTINOIDI
La US Food and Drug Administration (FDA) ha preteso l’inserimento di nuove avvertenze nelle schede tecniche del gabapentin (Neurontin-Pfizer; disponibile anche come medicinale equivalente) e del pregabalin (Lyrica-Pfizer; disponibile anche come medicinale equivalente) in merito al rischio di depressione respiratoria pericolosa per la vita o fatale nei pazienti che presentano fattori di rischio respiratori, (1) tra cui broncopneumopatia cronica ostruttiva (BPCO) e utilizzo concomitante di oppioidi o di altre sostanze che deprimono il SNC. Anche i pazienti anziani sono esposti a un rischio maggiore.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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