The Medical Letter TML n. 13/2020
Nr. 13 del 01/07/2020
TML n. 13/2020 EPTINEZUMAB PER LA PREVENZIONE DELL’EMICRANIA
La US Food and Drug Administration (FDA) ha approvato l’eptinezumab-jjmr (Vyepti-Lundbeck negli USA; non disponibile in commercio in Italia), un antagonista del peptide correlato al gene della calcitonina (CGRP) somministrato per via endovenosa una volta ogni tre mesi, per la prevenzione dell’emicrania negli adulti. Si tratta del quarto anticorpo monoclonale a essere approvato per questa indicazione; in precedenza sono stati approvati l’erenumab (Aimovig-Novartis Farma), il fremanezumab (Ajovy-Teva; il farmaco ha ottenuto l’autorizzazione all’immissione in commercio da parte dell’EMA tramite procedura centralizzata, ma non è ancora disponibile in commercio in Italia) e il galcanezumab (Emgality-Eli Lilly), i quali vengono tutti somministrati per via sottocutanea una volta al mese (il fremanezumab può anche essere somministrato una volta ogni tre mesi).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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