The Medical Letter TML n. 13/2020
Nr. 13 del 01/07/2020
TML n. 13/2020 UNA NUOVA ASSOCIAZIONE A TRE FARMACI PER IL DIABETE DI TIPO 2
La US Food and Drug Administration (FDA) ha approvato Trijardy XR (Boehringer Ingelheim/Eli Lilly negli USA; non disponibile in commercio in Italia), un’associazione precostituita dell’inibitore del co-trasportatore sodio-glucosio di tipo 2 (SGLT2) empagliflozin, dell’inibitore della dipeptidil peptidasi-4 (DPP-4) linagliptin e della metformina a rilascio prolungato, per il trattamento orale del diabete di tipo 2 negli adulti. L’empagliflozin e il linagliptin sono disponibili dal 2015 negli Stati Uniti e dal 2017 in Italia in un’associazione precostituita denominata Glyxambi (Boehringer Ingelheim) e da anni in associazioni a due farmaci con la metformina a rilascio prolungato
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