The Medical Letter TML n. 14/2011
Nr. 14 del 15/07/2011
TML n. 14/2011 – DESMEDETOMIDINA PER LA SEDAZIONE NELLE UNITÀ DI TERAPIA INTENSIVA
Gli oppioidi, le benzodiazepine, il propofol, gli antipsicotici e la desmedetomidina (Precedex-Hospira, in USA; non disponibile in commercio in Italia) vengono frequentemente utilizzati nelle Unità di Terapia Intensiva (UTI) per controllare il dolore, l’ansia, l’agitazione e lo stato confusionale acuto e per facilitare procedure come la ventilazione meccanica. Negli ultimi anni negli Stati Uniti si è assistito a un aumento dell’impiego della desmedetomidina, un farmaco ad azione centrale, agonista selettivo dei recettori alfa2-adrenergici, approvato dalla US Food and Drug Administration (FDA) nel 1999 (1). Sono stati pubblicati alcuni nuovi studi di confronto tra desmedetomidina e altri farmaci utilizzati per la sedazione nelle UTI.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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