The Medical Letter TML n. 16/2011
Nr. 16 del 15/08/2011
TML n. 16/2011 – LINAGLIPTIN – UN NUOVO INIBITORE DELLA DPP-4 PER IL DIABETE TIPO 2
Il linagliptin (Tradjenta-Boehringer Ingelheim/Lilly, in USA), il terzo inibitore orale dell’enzima dipeptidil peptidasi-4 (DPP-4), è stato approvato dalla US Food and Drug Administration (FDA) il 2 maggio 2011 per il trattamento del diabete tipo 2, sia in monoterapia sia in associazione a metformina, a una sulfonilurea o a pioglitazone. In Europa il linagliptin (nome commerciale Trajenta) è in attesa di approvazione definitiva dopo il parere positivo del CHMP (Committee for Medicinal Products for Human Use) dell’EMA del 23 giugno 2011.
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