The Medical Letter TML n. 19/2011
Nr. 19 del 01/10/2011
TML n. 19/2011 – NUOVE RACCOMANDAZIONI DI DOSAGGIO PER LA SIMVASTATINA
La US Food and Drug Administration (FDA) ha annunciato che sono state apportate delle modifiche sull’etichettatura e nel foglietto illustrativo della simvastatina con l’obiettivo di ridurre il rischio di miopatia. Le modifiche comprendono la restrizione dell’utilizzo della dose massima di 80 mg ai pazienti che utilizzano questo dosaggio da almeno 12 mesi senza segni di miopatia, e nuove raccomandazioni relative all’impiego della simvastatina in associazione ad altri farmaci (1). La simvastatina è disponibile come farmaco singolo (Sinvacor-Merck Sharp & Dohme, e altri; disponibile anche come medicinale equivalente) e in associazione precostituita con ezetimibe (Vytorin-Schering-Plough, e altri) e con niacina (Simcor-negli USA; non disponibile in commercio in Italia).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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