The Medical Letter TML n. 19/2012
Nr. 19 del 01/10/2012
TML n. 19/2012 – IN BREVE: Emtricitabina/tenofovir (Truvada) per la prevenzione dell’infezione da HIV
Truvada (Gilead Sciences) è un’associazione precostituita per uso orale contenente gli antivirali emtricitabina e tenofovir disoproxil fumarato frequentemente utilizzata per il trattamento dell’infezione da HIV (1); recentemente la FDA ha approvato l’emtricitabina/tenofovir anche come terapia profilattica pre-esposizione per ridurre il rischio di infezione da HIV-1 acquisita per via sessuale nei soggetti adulti ad alto rischio. È il primo farmaco approvato per questa indicazione. Dal 2011 i Centers for Disease Control and prevention (CDC) raccomandano l’impiego off-label di Truvada per la profilassi pre-esposizione in uomini che hanno rapporti sessuali con uomini (2).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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