The Medical Letter TML n. 20/2015
Nr. 20 del 15/10/2015
TML n. 20/2015 – POLIDOCANOLO PER LE VENE VARICOSE
La US Food and Drug Administration (FDA) ha approvato una formulazione in schiuma iniettabile dell’agente sclerosante polidocanolo (Varithena in USA; formulazione non disponibile in commercio in Italia) per il trattamento delle vene incompetenti e delle varici visibili del sistema della vena grande safena. È la prima terapia a base di schiuma a essere approvata per questa indicazione, ma il polidocanolo e altri sclerosanti vengono utilizzati da anni dai medici sotto forma di composti in formulazione schiumosa. Il polidocanolo è disponibile anche in formulazione liquida (Atossisclerol-Chemische Fabrik Kreussler &Co) per il trattamento delle vene più piccole. Il sodio tetradecilsolfato (Fibrovein-MacPharma) è approvato dalla FDA e in Italia in una formulazione liquida per l’uso nella terapia sclerosante.
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