The Medical Letter TML n. 23/2014
Nr. 23 del 01/12/2014
TML n. 23/2014 – VEDOLIZUMAB PER LA MALATTIA INFIAMMATORIA INTESTINALE
La FDA ha approvato il vedolizumab (Entyvio-Takeda, negli USA), un antagonista del recettore per l’integrina per somministrazione endovenosa, per il trattamento della colite ulcerosa o del morbo di Crohn di grado moderato-grave in pazienti adulti che non hanno risposto, che hanno cessato di rispondere, o che sono risultati intolleranti al trattamento standard. In Europa, il vedolizumab ha ottenuto l’autorizzazione all’immissione in commercio da parte della European Medicines Agency (EMA) il 22 maggio 2014; in Italia è in corso la procedura di prezzo e rimborso. Il natalizumab (Tysabri-Biogen Idec Italia), un altro antagonista del recettore per l’integrina, è disponibile da diversi anni per il trattamento del morbo di Crohn e della sclerosi multipla (1).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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