The Medical Letter TML n. 24/2011
Nr. 24 del 15/12/2011
TML n. 24/2011 – VEMURAFENIB PER IL MELANOMA METASTATICO
La US Food and Drug Administration (FDA) ha approvato il vemurafenib (Zelboraf-Genentech, negli USA), un inibitore delle chinasi, per il trattamento del melanoma non operabile o metastatico in pazienti portatori della mutazione V600E del gene BRAF, mutazione presente nel 30-60% dei melanomi. Un test approvato dalla FDA è in grado di rilevare la mutazione nel DNA prelevato dalle cellule del melanoma. Il vemurafenib è attualmente in corso di valutazione da parte delle autorità regolatorie europee.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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