The Medical Letter TML n. 25 / 2024
Nr. 25 del 09/12/2024
TML n. 25 / 2024 Un contraccettivo ormonale in compresse disintegrabili per via orale
La US Food and Drug Administration (FDA) ha approvato Femlyv (Millicent; non disponibile in commercio in Italia), una compressa disintegrabile per via orale contenente etinilestradiolo e noretisterone acetato, per la prevenzione della gravidanza nelle donne con un indice di massa corporea (IMC) ≤35 kg/m2 . È il primo contraccettivo ormonale disponibile in una formulazione in compresse disintegrabili per via orale. Negli Stati Uniti sono disponibili da anni compresse orali masticabili tradizionali contenenti etinilestradiolo e noretisterone acetato in un'ampia gamma di dosi, comprese quelle presenti nel Femlyv.
SCELTA DEI CONTRACCETTIVI – I dispositivi intrauterini (IUD) e l'impianto di etonogestrel (Nexplanon - Organon Italia) sono i metodi contraccettivi reversibili più efficaci, ma richiedono una visita in ambulatorio per il posizionamento e la rimozione. Anche i contraccettivi ormonali combinati e solo progestinici (compresse orali, cerotti transdermici, anelli vaginali) e il medrossiprogesterone acetato per via iniettabile sono molto efficaci per prevenire la gravidanza. (1)
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