The Medical Letter n. 3 / 2021
Nr. 03 del 01/02/2021
TML n.3 / 2021 METOCLOPRAMIDE SPRAY NASALE PER LA GASTROPARESI DIABETICA
La FDA ha approvato Gimoti (Evoke Pharma negli USA; non disponibile in commercio in Italia), una formulazione spray nasale dell’antagonista del recettore dopamina-2 (D2) metoclopramide per il sollievo dei sintomi negli adulti con gastroparesi diabetica acuta e ricorrente. La metoclopramide (Plasil-Sanofi e altri; disponibile anche come medicinale equivalente) è disponibile da anni in diverse formulazioni. È l’unico farmaco approvato dalla FDA per il trattamento della gastroparesi diabetica.
TRATTAMENTO STANDARD – La gastroparesi diabetica è una sindrome da svuotamento gastrico ritardato spesso accompagnata da nausea, vomito, gonfiore e dolore addominale superiore; sembra essere più comune nelle donne che negli uomini. Nella gestione del disturbo può essere utile il controllo della glicemia.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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