The Medical Letter n. 3 / 2021
Nr. 03 del 01/02/2021
TML n.3 / 2021 OPICAPONE, UN INIBITORE DELLA COMT PER LA MALATTIA DI PARKINSON
La FDA ha approvato l’opicapone (Ongentys-Neurocrine negli USA; disponibile in Europa dal 2016; Ongentys-Bial Italia), un inibitore della catecolo-O-metiltransferasi (COMT) ad azione periferica reversibile per uso orale come coadiuvante del carbidopa/levodopa negli adulti con malattia di Parkinson (PD) che vanno incontro a episodi “off”. È il terzo inibitore del COMT ad essere approvato per questa indicazione; tolcapone (Tasmar-Hofmann-La Roche negli USA; Tasmar-Meda Pharma in Italia) ed entacapone (Comtan-Novartis negli USA; Comtan-Orion Pharma in Italia) erano stati approvati in precedenza.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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