The Medical Letter TML n. 5/2012
Nr. 05 del 01/03/2012
TML n. 5/2012 – FENTANIL IN SPRAY NASALE PER IL DOLORE
La US Food and Drug Administration (FDA) ha approvato una formulazione di fentanil in spray nasale (Lazanda-Archimedes, negli USA; disponibile in commercio in Italia da maggio 2011 con il nome PecFent-Molteni) per il trattamento delle esacerbazioni transitorie di dolore (breakthrough pain, BTP; dolore episodico intenso) in pazienti oncologici adulti già trattati con oppioidi e che hanno sviluppato tolleranza alla terapia con oppioidi. Il fentanil è disponibile in commercio anche in formulazioni per uso endovenoso, intratecale, epidurale, transdermico e transmucosale orale (1). In Italia oltre a PecFent è disponibile un altro prodotto in spray nasale a base di fentanil (Instanyl-Nycomed).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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