The Medical Letter TML n. 5/2016
Nr. 05 del 01/03/2016
TML n. 5/2016 – IN BREVE: Nuove indicazioni per Harvoni
Harvoni (Gilead Sciences), un’associazione precostituita ad assunzione monogiornaliera degli agenti antivirali ad azione diretta ledipasvir e sofosbuvir, approvata dalla US Food and Drug Administration (FDA) nel 2014 per il trattamento dell’infezione da virus dell’epatite C (HCV) di genotipo 1 (1), è stato ora approvato negli Stati Uniti per l’uso in pazienti con infezione da HCV di genotipo 4, 5 o 6, e in pazienti che presentano un’infezione concomitante da HCV e HIV-1. Un ciclo di trattamento di 12 settimane con Harvoni più ribavirina è stato approvato come un’alternativa alla terapia di 24 settimane con il solo Harvoni per i pazienti cirrotici con infezione da HCV di genotipo 1 già sottoposti a trattamento.
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