The Medical Letter n. 7 / 2021
Nr. 07 del 01/04/2021
TML n.7 / 2021 BAMLANIVIMAB ED ETESEVIMAB PER LA COVID-19
La Food and Drug Administration (FDA) ha rilasciato l’autorizzazione all’uso d’emergenza (EUA) per gli anticorpi monoclonali sperimentali di Lilly bamlanivimab (LY-CoV555) ed etesevimab (LY-CoV016), da somministrare insieme per il trattamento della COVID-19 da lieve a moderata in pazienti di età pari o superiore a 12 anni e peso pari o superiore a 40 kg, ad alto rischio di progressione verso una condizione grave e/o il ricovero ospedaliero (vedi Tabella 1). L’EMA ha avviato la revisione ciclica (rolling review), in quanto non ha ancora valutato la serie completa di dati e ritiene prematuro trarre conclusioni sul rapporto benefici/rischi. Il bamlanivimab aveva ottenuto la procedura EUA per l’uso in monoterapia in questa classe di pazienti nel novembre 2020.
Anche gli anticorpi monoclonali sperimentali di Regeneron casirivimab (REGN10933) e imdevimab (REGN10987) sono stati autorizzati per l’uso in somministrazione contemporanea per la stessa indicazione.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
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