The Medical Letter n. 7 / 2021
Nr. 07 del 01/04/2021
TML n.7 / 2021 SEMAGLUTIDE PER LA PERDITA DI PESO
In alcuni studi clinici di recente pubblicazione, l’iniezione sottocutanea una volta alla settimana dell’agonista del recettore del peptide 1 glucagone-simile (GLP-1) semaglutide (Ozempic-Novo Nordisk), approvato dalla FDA per il trattamento del diabete di tipo 2 e per la riduzione del rischio di eventi cardiovascolari avversi maggiori in adulti con diabete di tipo 2 e malattia cardiovascolare accertata, ha ridotto significativamente il peso corporeo in pazienti con e senza diabete di tipo 2 quando somministrato in aggiunta al cambiamento dello stile di vita.La liraglutide (Saxenda-Novo Nordisk), un altro agonista del recettore GLP-1, è stata approvata dalla FDA per la gestione cronica del peso nel 2015.
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