The Medical Letter TML n. 7/2015
Nr. 07 del 01/04/2015
TML n. 7/2015 – UN’ASSOCIAZIONE DI 4 FARMACI PER L’EPATITE C
La US Food and Drug Administration (FDA) ha approvato Viekira Pak (Abbvie in USA; non disponibile in commercio in Italia), un nuovo prodotto che include due tipi di compresse: un’associazione precostituita di due nuovi agenti antivirali ad azione diretta (ombitasvir, paritaprevir) con il potenziatore farmacologico ritonavir in una compressa, e un terzo nuovo agente antivirale ad azione diretta (didasabuvir) in una seconda compressa, per il trattamento orale dell’infezione cronica da virus dell’epatite C (HCV) di genotipo 1. Il genotipo 1 è responsabile del 70-80% dei casi di infezione da HCV negli Stati Uniti.
In Italia sono disponibili come farmaci ad esclusivo uso ospedaliero e sottoposti a monitoraggio addizionale Viekirax-Abbvie (cpr contenenti 12,5 mg di ombitasvir + 75 mg di paritaprevir + 50 mg di ritonavir) ed Exviera-Abbvie (cpr riv da 250 mg di didasabuvir).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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