The Medical Letter TML n. 7/2016
Nr. 07 del 01/04/2016
TML n. 7/2016 – ROLAPITANT PER LA PREVENZIONE DI NAUSEA E VOMITO TARDIVI INDOTTI DA CHEMIOTERAPIA
La US Food and Drug Administration (FDA) ha approvato il rolapitant (non disponibile in commercio in Italia), un antagonista orale dei recettori della sostanza P/neurochinina 1 (NK1), per l’uso con altri antiemetici nella prevenzione di nausea e vomito tardivi associati alla chemioterapia antitumorale negli adulti. Si tratta del terzo antagonista dei recettori della sostanza P/NK1 a essere approvato negli Stati Uniti; l’aprepitant (Emend-MSD Italia) e il netupitant (disponibile solo in associazione all’antagonista dei recettori 5-HT3 palonosetron come Akynzeo-Helsinn/Eisai negli Stati Uniti; approvato in Europa, ma non disponibile in commercio in Italia) sono stati approvati in precedenza per la prevenzione di nausea e vomito acuti e tardivi indotti da chemioterapia (1, 2).
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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