The Medical Letter TML n. 8 / 2022
Nr. 08 del 18/04/2022
TML n. 8 / 2022 NUOVA INDICAZIONE DI EMPAGLIFLOZIN PER L’INSUFFICIENZA CARDIACA
Nel 2021 la Food and Drug Administration (FDA) ha approvato l’inibitore del cotrasportatore sodio-glucosio 2 (SGLT2) empagliflozin (Jardiance-Boehringer Ingelheim) per ridurre il rischio di ospedalizzazione per insufficienza cardiaca (HF) e morte cardiovascolare nei pazienti con insufficienza cardiaca e frazione di eiezione ridotta (HFrEF; LVEF ≤ 40%), indipendentemente dal fatto che siano o meno affetti da diabete di tipo 2.
L’indicazione è stata ora ampliata a includere i pazienti con HF e qualsiasi valore di frazione di eiezione. Empagliflozin è il primo inibitore del SGLT2 a essere approvato negli Stati Uniti per questa indicazione.
INIBITORI DEL SGLT2 E INSUFFICIENZA CARDIACA – Tutti gli inibitori del SGLT2 attualmente disponibili hanno dimostrato di ridurre il rischio di ospedalizzazione per insufficienza cardiaca di circa il 30% nei pazienti con diabete di tipo 2.
Questo è l'abstract dell'articolo. Per poter consultare l'intero numero o più numeri scegli il tipo di abbonamento che preferisci.
Se sei già abbonato accedi.
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