The Medical Letter TML n. 8/2014
Nr. 08 del 15/04/2014
TML n. 8/2014 – DAPAGLIFLOZIN PER IL DIABETE TIPO 2
Il dapagliflozin (Farxiga-Bristol-Myers Squibb/AstraZeneca, negli USA; Forxiga in Europa), un inibitore del SGLT2 (cotrasportatore del sodio-glucosio di tipo 2), è stato approvato dalla US Food and Drug Administration (FDA) per il trattamento orale del diabete tipo 2. Il dapagliflozin è il secondo inibitore del SGLT2 approvato per questa indicazione, dopo il canagliflozin (Invokana-Janssen, negli USA)1. Il dapagliflozin e il canagliflozin sono stati approvati in Europa rispettivamente nel novembre 2012 e novembre 2013 e non sono attualmente in commercio in Italia.
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